Tablet Presentation

Each film coated tablets contains:

Ursodeoxycholic Acid BP       300/600 mg

Ursodeoxycholic acid is also known as ursodiol. It is the precursor of the chenodeoxycholate . It is used as the cholagogue and choleretic. It is also known as the secondary bile acid.

Indication

• It is used to decrease the absorption of cholesterol
• It is used to dissolves the gallstones

Mechanism of action

It reduces the increased level of liver enzyme and promotes the flow of bile through liver or prevent the liver cells, it get concentrated over there and prevent the synthesis of cholesterol in the liver and inhibit the intestinal absorption of the cholesterol.

Pharmacokinetics

Absorption- It is absorbed rapidly from the GIT-
Protein binding- It is about 98% bound to serum protein
Metabolism- It undergoes conjugation in the liver
Excretion– It is excreted via feces

Side effects

• Nausea
• Vomiting
• Diarrhea
• Deposition of calcium in the gallstones

Contraindications

• Contraindicated in pregnant women
• Contraindicated in liver problems

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