Each film coated tablets contains:
|Etodolac IP 400 mg |
Etodolac (SR) IP 500 mg
- Rheumatoid arthritis
- Acute Pain
- Juvenile rheumatoid arthritis
Mechanism of action
It works by blocking the cox-1and cox-2 enzymes which is involve in the production of prostaglandins which mediates inflammation, fever ,As this enzyme converts arachidonic acid to prostaglandins therefore, it inhibits it.
It is absorbed orally
It is about 99.9% bound to serum albumin
It is metabolized in the liver and undergoes hydroxylation and glucuronide conjugation.
It is excreted in unchanged form in the urine.
- Contraindicated in patients with known hypersensitivity and allergy.
- Contraindicated during the third trimester of pregnancy.
Store it at room temperature.