Olmesartan Tablet

Packing Available

Tablet Presentation

Each film coated tablets contains:
Olmesartan Medoxomil IP           20 mg
Olmesartan Medoxomil IP           40 mg

Olmesartan medoxomil belongs to the class of angiotensin - 2 receptor blocker. It is used in the management of the hypertension .


  • Hypertension
  • Rise in blood pressure due to diseases like stroke, kidneys problems, heart attacks
  • Type -2 diabetes associated with nephropathy.

Mechanism of Action

Olmesartan blocks the RAAS system which plays important role in maintaining hemostatis , regulation of the kidney , vascular functions . olmesartan inhibits activation of RAAS system by blocking the AT1 receptor which inhibits binding of the angiotensin to angiotensin receptor i.e AT1 and prevents the angiotensin -2 mediated effects such as vasoconstriction, synthesis of aldosterone , renal absorption of sodium .


Absorption: Its absorption is rapid and complete from the GI tract
Protein binding: It is about 99% bound to plasma proteins
Metabolism: It is metabolized to olmesartan and undergoes ester hydrolysis
Excretion: It is excreted unchanged in the urine.

Side Effects

  • Decrease urination
  • Mild headache
  • Increase heart rate
  • Swelling in the hands and feet
  • Nausea


  • Contraindicated in pregnancy
  • Contraindicated in renal artery stenosis
  • Contraindicated in acute kidney failure
Know About new DCGI Approved Products