Tablet Presentation

Each film coated tablets contains:
Omeprazole Magnesium IP             10 mg
Ondansetron Hydrochloride IP        4 mg

Omeprazole proton pump inhibitor. It is used to treat gastric acid related disorders such as gastroesophageal reflux disease, peptic ulcer and over secretion of gastric acid. It is very effective among other PPI 's and is well tolerated .
Ondansteron is the serotonin 5HT3 antagonist.It is used in the treatment of the Vomiting and nausea


    This combination is used to treat chemotherapy induced nausea and vomiting.

Mechanism of Action


It mainly blocks the 5HT3 receptors located in the nerve terminals in the vagus in the periphery and in the chemotrigger zone, area of postrema .


Hcl production is regulated by H+ K+ ATPase of the protein pump inhibitor present in the parietal cells so omaprazole covalently bind to cysteine residue of the alpha subunit of the H+ K+ ATPase pump and inhibits the over production of hcl.


Ondansetron Hydrochloride:

Absorbtion: It is absorbed by oral route.
Protein binding: It is about 73% bound to plasma proteins.
Metabolism: It is metabolized in the liver with the help of cytochrome enzymes and undergoes conjugation and hydroxylation.
Excretion: It is excreted by urine in unchanged form


Absorption: omeprazole is rapidly absorbed from the stomach.
Protein binding: omeprazole is about 95% bound to plasma proteins.
Metabolism: It is metabolized in the liver.
Excretion: It is eliminated from the urine and rest of the drug is excreted via feces.

Side Effects

  • Stomachache
  • Nausea
  • vomiting
  • Flatulence
  • Constipation
  • Diarrhea
  • Headache


Contraindicated in people with known hypersensitivity.


It is stored at room temperature
Know About new DCGI Approved Products