Syrup Presentation

Each Reconstituted 5 ml contains :
Cefpodoxime Proxetil IP        50 mg

Dry syrups are the mixtures that require the addition of water at the time of dispensing inadequate chemical stability of drug in aqueous vehicle to avoid the physical stability problem.
Cefpodoxime is cephalosporin antibiotic it is act as bactericide. It is used in the respiratory infections, ear infections, urinary tract infections

Indications

• Treats respiratory tract infection
• Urinary tract infection
• In ear infections
• Treats skin infections

Mechanism of Action

Cefpodoxime is broad spectrum cephalosporin active against Gram-positive and Gram-negative bacteria and is resistant to beta-lactamase enzymes. Cefpodoxime is inactivated by beta-lactamases enzymes. Cefpodoxime inhibits cell wall synthesis and exhibits bactericidal action. cefpodoxime binds with penicillin binding protein 3, which inhibits the synthesis of peptidoglycan, the main constituent of bacterial cell.

Side Effects

• Bloody stools
• Seizures
• Rashes
• Itching
• Stomach pain

Contraindications

• Contraindicated in people with known hypersensitivity to cephalosporin
• Contraindicated in people if one is experience seizures against the drug

Pregnancy: only used if needed

Storage

Store this syrup at cool place

Drug Interactions

• Probenecid
• Antiviral drugs