Cyproheptadine Tablet

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Tablet Presentation

Each Uncoated Tablet Contains:
Cyproheptadine Hydrochloride IP
eq. to Cyproheptadine HCl anhydrous 4 mg

Cyproheptadine is histamine blocker, it also blocks serotonin
It produces antiemetic effect by blocking the central muscarinic receptors


  • Allergic rhinitis
  • Allergic conjunctivitis
  • Migraine

Mechanism of action

It competitively inhibits the binding of the free histamine to its receptor and prevents its negative symptom, cyproheptadine also inhibits the serotonin in smooth muscles of the small intestine thus stimulates appetite


Absorption: It is absorbed by the oral route of administration
Protein binding: It is 99.9% bound to plasma proteins
Metabolism: It is metabolized in the liver
Excretion: It is excreted via urine

Side Effects

  • Drowsiness
  • Dizziness
  • Insomnia
  • Blurring of vision
  • Loss of coordination


  • Contraindicated in closed angle glaucoma
  • Contraindicated in high blood pressure
Pregnancy: Used only if benefits outweighs the risk


Store it at room temperature
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