Syrup Presentation

Each 5 ml Contains:
Ammonium Chloride 60 mg
Chlorpheniramine Maleate 2.5 mg
Dextromethorphan 5 mg
Guaiphenesin 50 mg

This combination of compounds is commonly used to provide relief against the cough and allergic symptoms.

Indications

• Running nose
• Sneezing
• Watery Eyes
• Cough Suppressant

About Composition

Dextromethorphan Hydrobromide:

Dextromethorphan suppresses medullary cough centre and is an NMDA receptor antagonist (receptors, N-methyl-D-aspartate). It acts as a non- competitive channel blocker and is one of the widely used antitussives Dextromethorphan is categorized as an opioid drug that acts as antagonist to the NMDA glutamatergic receptor.

Chlorpheniramine Maleate:

Diphenhydramine acts on histamine H1 receptor as an inverse agonist. It structurally resembles the ethanolamine class of antihistaminergic agents. By antagonising the effects of histamine on the capillaries, it can reduce the tenseness of allergic symptoms. It also acts centrally as it crosses the blood–brain barrier and inversely agonizes the H 1 receptors which can result in drowsiness.

Guaiphenesin:

Guaifenesin is as an expectorant that acts by enhancing the removal of sputum and bronchial secretions by decreasing the adhesiveness and surface tension of sputum to the respiratory tract

Ammonium Chloride:

Ammonium chloride can be used as an expectorant. It works by causing irritative action on the bronchial mucosa thus causes the production of respiratory tract fluid which in order facilitates the effective cough.

Side Effects

• Nausea
• Vomiting
• Sleepiness
• Dizziness
• Headache
• Rashes
• Hives

Contraindications

Contraindicated in patients with known hypersensitivity

Storage

Store it in cool place