Each Film Coated Tablet Contains:
Fenofibrate IP (Micronised) 200 mg
Fenofibrate belongs to the class of fibrates and is used with low fat food or other drugs to reduce the fatty substances such as cholesterol and circulating triglycerides in the blood or to increase the level of HDL (good fat).
- severe hypertriglyceridemia
Mechanism of action
Fenofibrate activates the PPAR-alpha receptors that further activates the gene transcription and gene translation to produce peroxisomes contains Hydroxyl Radicals , hydrogen peroxide, oxygen reactive species to promote lipolysis.
It is absorbed orally
It is mainly bound to albumin and it is about 99.9% bound to serum proteins
It undergoes hydroxylation and glucuronidation
It is excreted via urine
- Dark urine
- Yellowing of the eyes
- Contraindicated in the patients with renal impairment
- Contraindicated in patients with liver disease
Store this drug at room temperature.
Not recommended to use during pregnancy