Tablet Presentation

Each Combikit Contains:


  • Vaginal yeast infections
  • Systemic candida infection
  • Cryptococcal meningitis
  • Peritonitis
  • Urinary tract infection
  • Tonsillitis
  • Pneumonia

About Composition


Azithromycin is a broad-spectrum macrolide antibiotic. It is used in the treatment of the respiratory tract infection, genitourinary tract infection.


Fluconazole is the antifungal drug. It is used to treat systemic and superficial fungal infections. It is mainly efficacious in the treatment of vaginal yeast infection


Secnidazole is the 5-nitroimdazole antimicrobial agent. It is effective against anaerobic gram positive and gram-negative bacteria

Mechanism of action

Azithromycin inhibits the protein synthesis by binding with the 23S rRNA of the 50 s ribosomal unit of the RNA and inhibit the translocation step in the protein synthesis.

Fluconazole is inhibiting the enzyme lanosterol 14-alpha demethylase which is responsible for the conversion of the lanosterol to ergosterol which is the essential component for the cell wall synthesis of fungi

Secnidazole is a prodrug. It is converted to an active metabolite by reducing the nitro group into anion by bacterial enzymes which then interfere with the DNA synthesis in the bacteria



Absorption: It is orally absorbed.
Protein binding: It is bound to proteins to lesser extend.
Metabolism: It is metabolized in the liver.
Excretion: It is excreted via urine.


Absorption: It is absorbed orally and produce bioavailability up to 90%.
Protein binding: protein binding of fluconazole is low.
Metabolism: Fluconazole is undergoing glucuronide conjugation.
Excretion: It is excreted unchanged in the urine


Absorption: It is completely absorbed by oral route.
Protein binding: protein binding is 5-15%.
Metabolism: It is metabolised by oxidation reaction.
Excretion: It is excreted unchanged in the urine

Side Effects

  • Headache
  • Nausea
  • Abdominal pain
  • Itching or discomfort in the vagina


  • Contraindicated in the people with known hypersensitivity.
  • Contraindicated during the third trimester of pregnancy


Store it below 30°C

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